Craniosynotosis - Mental Retardation - Clefting Syndrome is a rare form of intellectual disability characterized by early fusion of the skull bones, below-average mental ability, and an opening in the roof of the mouth or the lip. Early fusion of the skull bones can lead to problems with brain development. Hence, individuals with this disorder develop intellectual disability. The mouth and lip openings can also cause eating as well as breathing problems. Individual may also have problems with reasoning and solving problems, as well as performing day-to-day tasks. The disorder is often diagnosed early in childhood, since the symptoms are very apparent. Slow mastering of basic tasks, and having difficulty remembering things may also suggest this disorder in children. Treatment is developed on a case-by-case basis and depends on the specific needs of the patient. Doctors may suggest patients undergo surgery to close the mouth opening. Doctors seek help from various therapists and community services to provide support and care for families affected by intellectual disability.