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Factor VIII deficiency

Hemophilia AClassic hemophilia
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 111 results.
A Phase 3, Open-label Interventional Study of an Intravenous Recombinant Coagulation Factor VIII Fc-von Willebrand Factor-XTEN Fusion Protein, BIVV001, in Patients With Severe Hemophilia A (XTEND-1)
Status: Recruiting
Last Changed: Jan 18, 2020
First Received: Nov 13, 2019
Disease(s): Factor VIII Deficiency
Intervention(s): BIVV001
Locations: Investigational Site Number 906, Las Vegas, Nevada, United States
An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment
Status: Recruiting
Last Changed: Jan 21, 2020
First Received: Nov 15, 2019
Disease(s): Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor, Haemophilia A
Intervention(s): Standard of Care for Haemophilia A
Locations: Az. Osp. Pugliese Ciaccio; S. C. Emofilia, Emostasi e Trombosi, Catanzaro, Calabria, Italy
Azienda Ospedaliera di Cosenza - P.O. Annunziata; UO Patologie della Coaugulazione, Cosenza, Calabria, Italy
AOU Federico II; Medicina Clinica Chirurgia Centro Emocoaugulopatie e Emofilia, Napoli, Campania, Italy
PO Cesena - Osp M. Bufalini; Patologia Clinica - S.S.A. Serv. Medicina Trasf.- Centro Emofilia, Cesena, Emilia-Romagna, Italy
Universita' Degli Studi La Sapienza-Ist.Di Ematologia; Dip Biot Cel e Ematol, Roma, Lazio, Italy
... and 12 other locations.
A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors
Status: Recruiting
Last Changed: Jan 13, 2020
First Received: Nov 12, 2019
Disease(s): Mild Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor, Hemophilia A
Intervention(s): Emicizumab
Locations: Childrens Hospital LA, Los Angeles, California, United States
Georgetown Uni Medical Center; Lombardi Cancer Center, Washington, District of Columbia, United States
Hemophilia of Georgia Center for Bleeding & Clotting Disorders, Decatur, Georgia, United States
Indiana Hemophilia & Thrombosis center, Indianapolis, Indiana, United States
University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, Michigan, United States
... and 21 other locations.
Pharmacokinetic Characterization of the Hemophilia A Population in Spain Using myPKFiT®
Status: Recruiting
Last Changed: Nov 27, 2018
First Received: Dec 30, 2016
Disease(s): Hemophilia A, Hemophilia, Factor VIII Deficiency
Intervention(s): Octocog Alfa
Locations: Complexo Hospitalario Universitario A Coruña, A Coruna, A Coruña, Spain
Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Hospital Sant Joan de Deu, Esplugues de Llobregat, Barcelona, Spain
Hospital Universitario Son Espases, Palma, Islas Baleares, Spain
Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain
... and 10 other locations.
Factor VIII Gene Therapy Study in Patients With Hemophilia A
Status: Recruiting
Last Changed: Jan 07, 2020
First Received: Jul 17, 2018
Disease(s): Hemophilia A
Intervention(s): BAY2599023 (DTX201)
Locations: Arkansas Children's Hospital, Little Rock, Arkansas, United States
Loma Linda Children's Hospital, San Bernardino, California, United States
C.S. Mott Children's Hospital, Ann Arbor, Michigan, United States
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
University of Wisconsin - Madison, Madison, Wisconsin, United States
... and 21 other locations.
Emicizumab in Acquired Hemophilia A
Status: Not yet recruiting
Last Changed: Dec 09, 2019
First Received: Dec 06, 2019
Disease(s): Hemophilia A, Acquired
Intervention(s): Emicizumab Injection
Drug Use Investigation of Kovaltry in Hemophilia A Patients
Status: Recruiting
Last Changed: Jan 22, 2020
First Received: Oct 21, 2016
Disease(s): Hemophilia A
Intervention(s): Kovaltry (Antihemophilic Factor [Recombinant], BAY81-8973)
Locations: Many Locations, Multiple Locations, Japan
Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A
Status: Recruiting
Last Changed: Oct 18, 2019
First Received: Oct 18, 2019
Disease(s): Hemophilia A
Intervention(s): assessment of joint health and bone density
Locations: Orthopedic Hemophilia Treatment Center, Los Angeles, California, United States
Hemophilia and Thrombosis Treatment Center, University of California, San Diego, San Diego, California, United States
Tulane University, New Orleans, Louisiana, United States
Washington Center for Bleeding Disorders at Bloodworks NW, Seattle, Washington, United States
Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
Status: Not yet recruiting
Last Changed: Dec 20, 2019
First Received: Jan 28, 2019
Disease(s): Hemophilia A
Intervention(s): Auto CD34+PBSC, transduced with a lentiviral vector encoding the B domain deleted from of human coagulation factor VIII
A Gene Transfer Study for Hemophilia A
Status: Recruiting
Last Changed: Mar 13, 2019
First Received: Dec 28, 2016
Disease(s): Hemophilia A
Intervention(s): SPK-8011
Locations: University of California Davis - Hemostasis and Thrombosis Center, Sacramento, California, United States
Boston Children's Hospital, Boston, Massachusetts, United States
Mississippi Center for Advanced Medicine, Madison, Mississippi, United States
Weill Cornell Medicine-Comprehensive Center for Hemophilia and Coagulation Disorders, New York, New York, United States
East Carolina University, Greenville, North Carolina, United States
... and 7 other locations.