Acquired ichthyosis, also known as ichthyosis acquisita, is a condition similar to ichthyosis vulgaris, which causes dead skin cells to accumulate in thick, dry scales on your skin's surface. Unlike ichthyosis vulgaris however, acquired ichthyosis is not hereditary but instead associated with internal disease. It may develop in patients of any age with certain forms of malignant (cancerous) disease and infectious diseases; in dietary and vitamin deficiencies (for example Vitamin A deficiency); as a side-effect of cholesterol-lowering drugs; in dialysis patients; and also sometimes with no obvious underlying cause. It has most frequently been reported in association with Hodgkin’s lymphoma, a type of cancer affecting the blood cells. Acquired ichthyosis may also occur in patients suffering from leprosy, tuberculosis, AIDS and typhoid fever.