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Mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-5 of 5 results.
L-Citrulline Dose Finding Safety Study in MELAS
Status: Not yet recruiting
Last Changed: Jul 20, 2020
First Received: May 16, 2019
Disease(s): MELAS Syndrome
Intervention(s): L-Citrulline
Locations: Baylor St. Luke'S Medical Center, Houston, Texas, United States
A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
Status: Recruiting
Last Changed: Mar 25, 2019
First Received: Mar 25, 2019
Disease(s): Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies, MELAS Syndrome, Mitochondrial Myopathies
Intervention(s): KL1333, Placebo Oral Tablet
Locations: Covance Leeds, Leeds, West Yorkshire, United Kingdom
Phase 2a Study of IW-6463 in Adults Diagnosed With MELAS
Status: Not yet recruiting
Last Changed: Jul 27, 2020
First Received: Jul 17, 2020
Disease(s): MELAS
Intervention(s): IW-6463 Tablets
Status: Recruiting
Last Changed: Jun 22, 2020
First Received: Nov 15, 2019
Disease(s): Mitochondrial Diseases, Mitochondrial Myopathies, Mitochondrial Encephalomyopathies, MELAS Syndrome, MIDD
Intervention(s): KH176, KH176, Placebo
Locations: Friedrich-Baur Institut, München, Bayern, Germany
Radboud University Medical Center, Nijmegen, Netherlands
Institute for Ageing and Health Newcastle University, Newcastle upon Tyne, United Kingdom
Nicotinamide Riboside and Mitochondrial Biogenesis
Status: Recruiting
Last Changed: Jul 08, 2019
First Received: Feb 14, 2018
Disease(s): Mitochondrial Diseases, Mitochondrial Myopathies, Progressive External Ophthalmoplegia, Progressive Ophthalmoplegia, Progressive; Ophthalmoplegia, External, Mitochondria DNA Deletion, MELAS, Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes, Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Intervention(s): Nicotinamide Riboside
Locations: Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom