Progressive supranuclear ophthalmoplegia is a disease affecting movement of the eyes. Symptoms of the condition include being unable to move the eyes in all directions (especially upward), as well as mild dementia and stiff and uncoordinated movements. Progressive supranuclear ophthalmoplegia is often caused by progressive supranuclear palsy (PSP), a condition that affects the way the brain controls movement.
Other diseases can also cause progressive supranuclear ophthalmoplegia such as encephalitis (inflammation of the brain), olivopontocerebellar atrophy (shrinking of the cerebellar portion of the brain), amyotrophic lateral sclerosis (nerve cell disease affecting movement), and Whipple disease (disease affecting the lining of the small intestine).
Diagnosis of progressive supranuclear ophthalmoplegia involves performing a physical exam and focusing on the symptoms of the eyes and nervous system. Additional tests may be done to check for the diseases that are linked to the condition.
Treatment depends on the specific symptoms present and the underlying cause of the condition. If you or a family member has been diagnosed with progressive supranuclear ophthalmoplegia, talk to your doctor about the most current treatment options. Support groups are also a good source of information.
Description Last Updated: Aug 29, 2018